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MOG 35-55
来源:
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作者:jienitai
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发布时间: 2019-03-11
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233 次浏览
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分享到:
MEVGWYRSPFSRVVHLYRNGK
MOG 35-55
| 货号 | 数量 | 价格（元） | 货期 | ||
| GEB200301 | 5 mg | 询价 | 1~2天 | ||
| GEB200302 | 10 mg | 询价 | 1~2天 | ||
| GEB200303 | 20 mg | 询价 | 1~2天 | ||
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| 别名： | Myelin Oligodendrocyte Glycoprotein(35-55) | ||||
| 纯度： | >98% | ||||
| 序列： | MEVGWYRSPFSRVVHLYRNGK | ||||
| Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys | |||||
| CAS No.: | 149635-73-4 | ||||
| 分子式： | C118H177N35O29S | ||||
| 分子量： | 2581.99 | ||||
| 外观： | 白色粉末 | ||||
| 盐： | TFA | ||||
| 溶解性： | 易溶于水 | ||||
| 储存条件(冻干粉)： | -20°C（1年） 或 -80°C（1-2年） | ||||
| 运输条件： | 常温（加冰袋） | ||||
| 描述： | 髓鞘少突胶质细胞糖蛋白（MOG）是免疫球蛋白超家族的一员，仅在中枢神经系统（1-3）中表达?？梢鸸惴旱纳窬低惩阉枨剩?-55）抗体释放。在多发性硬化（MS）患者、MOG（35-55）诱导的实验性自身免疫性脑脊髓炎（EAE）C57/BL6小鼠和Lewis大鼠（1-4）中观察到了对MOG（35-55）的自身抗体反应 | ||||
| 结构图： |
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| 参考资料： |
1, Induction of a multiple sclerosis-like disease in
mice with an immunodominant epitope of myelin oligodendrocyte
glycoprotein Anthony Slavin, Christine Ewing, Junliang Liu, Motoki Ichikawa, John Slavin & Claude C.A. Bernard; Journal of Autoimmunity; Volume 28, 1998 - Issue 2 2, IgG Subclass Switching Is Associated with the Severity of Experimental Autoimmune Encephalomyelitis Induced with Myelin Oligodendrocyte Glycoprotein Peptide in NOD Mice Motoki Ichikawa, Chang-Sung Koh, Yuji Inaba, Chinatsu Seki, Atsushi Inoue, Makoto Itoh, Yoshihiro Ishihara, Claude C.A.Bernard, Atsushi Komiyama; Cellular Immunology; Volume 191, Issue 2, 1 February 1999, Pages 97-104 3, Myelin Oligodendrocyte Glycoprotein–specific T Cell Receptor Transgenic Mice Develop Spontaneous Autoimmune Optic Neuritis Estelle Bettelli, Maria Pagany, Howard L. Weiner, Christopher Linington, Raymond A. Sobel, Vijay K. Kuchroo; J Exp Med (2003) 197 (9): 1073–1081 4, Activation of invariant NKT cells by αGalCer administration protects mice from MOG35–55‐induced EAE: critical roles for administration route and IFN‐γ Roberto Furlan, Alessandra Bergami, Daniela Cantarella, Elena Brambilla, Masaro Taniguchi, Paolo Dellabona, Giulia Casorati, Gianvito Martino; The European Journal of Immunology; Volume 33, Issue 7,July 2003 |
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