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Beta-Amyloid 25-35 | Aβ 25-35
来源:
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作者:jienitai
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发布时间: 2020-10-03
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16 次浏览
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分享到:
GSNKGAIIGLM
Beta-Amyloid 25-35 | Aβ 25-35
| 货号 | 数量 | 价格（元） | 货期 | ||
| A-25-35-T-1 | 1 mg | ￥200.00 | 1~2天 | ||
| A-25-35-T-5 | 5 mg | 询价 | 1~2天 | ||
| A-25-35-T-10 | 10 mg | 询价 | 1~2天 | ||
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| 英文别名： | Aβ 25-35 | Aβ 25-35 | Abeta 25-35 | Amyloid-β 25-35 | β-Amyloid 25-35 | ||||
| 中文名： | β-淀粉样多肽 25-35 | Beta-淀粉样多肽 25-35 | Beta-淀粉样多肽 25-35 | Β-淀粉样多肽 25-35 | Beta-Amyloid多肽 25-35 | ||||
| 纯度： | >95% by HPLC | ||||
| 序列(单字母)： | GSNKGAIIGLM | ||||
| (三字母序列)： | Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met | ||||
| CAS No.： | 131602-53-4 | ||||
| 分子式： | C45H81N13O14S | ||||
| 分子量： | 1060.28 | ||||
| 外观： | 白色粉末 | ||||
| 等电点： | 10.1 | ||||
| 净电荷(PH=7)： | 1.0 | ||||
| 平均亲水性： | -0.3 | ||||
| 亲水残基比例： | 27% | ||||
| 盐： | TFA | ||||
| 来源： | 化学合成 | ||||
| 储存条件(冻干粉)： | -20°C（1年） 或 -80°C（1-2年） | ||||
| 溶解条件： | Acetic acid/water (3:2) or DMSO | ||||
| 运输条件： | 常温（加冰袋） | ||||
| 描述： | The fragment Aβ(25–35) of the Alzheimer's amyloid β -peptide, like its full-length peptide Aβ(1–42), has shown neurotoxic activities in cultured cells. But it differs from all the other commonly studied β-amyloid peptides because of its extremely rapid aggregation properties and enhanced neurotoxicity.Aβ(25–35) is able to cause memory impairment and neurodegenerative events. | ||||
| 分子结构： |
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| 参考： |
1, Rapid aggregation and
assembly in aqueous solution of Aβ (25–35) peptide. Lia Millucci, Roberto Raggiaschi, Davide Franceschini, Georg Terstappen & Annalisa Santucci; Journal of Biosciences volume 34, pages293–303(2009) 2, Aβ(25–35) peptide displays H2O2-like reactivity towards aqueous FE2+, nitroxide spin probes, Ant) synaptosomal membrane proteins. D.Allan Butterfield; LauraMartin John M.Carney; Kenneth Hensley. Life Sciences, Volume 58, Issue 3, 8 December 1995, Pages 217-228 3, Aβ (25–35) and its C‐and/or N‐blocked derivatives: Copper driven structural features and neurotoxicity Maria Laura Giuffrida Giulia Grasso Menotti Ruvo Carlo Pedone Angela Saporito Daniela Marasco Bruno Pignataro Claudia Cascio Agata Copani Enrico Rizzarelli. Neuroscience Research; Volume 85, Issue 3 15 February 2007. Pages 623-633 |
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